Article
Fatal venlafaxine poisonings are associated with a high prevalence of drug interactions.
International journal of legal medicine - 1 May 2011
Launiainen Terhi, Rasanen Ilpo, Vuori Erkki, Ojanperä Ilkka
Abstract excerpt
Venlafaxine (VEN) is an antidepressant found to possess a higher fatal toxicity index (FTI, i.e., deaths in proportion to consumption) than other newer antidepressants and selective serotonin reuptake inhibitors (SSRIs). The aim of this study was to elucidate using post-mortem cases whether the apparent high toxicity of VEN is associated with adverse drug interactions, pharmacogenetic factors and/or the manner of...
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