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Article

Identification and characterization of a type III polyketide synthase involved in quinolone alkaloid biosynthesis from Aegle marmelos Correa.

The Journal of biological chemistry - 8 Mar 2013

Resmi Mohankumar Saraladevi, Verma Priyanka, Gokhale Rajesh S, Soniya Eppurathu Vasudevan

Abstract excerpt

Quinolone alkaloids, found abundantly in the roots of bael (Aegle marmelos), possess various biological activities and have recently gained attention as potential lead molecules for novel drug designing. Here, we report the characterization of a novel Type III polyketide synthase, quinolone synthase (QNS), from A. marmelos that is involved in the biosynthesis of quinolone alkaloid. Using homology-based structural...

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Identifiers

PMID: 23329842
DOI: 10.1074/jbc.M112.429886
PMCID: PMC3591635

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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