Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of the orsellinic acid synthase PKS63787 for the biosynthesis of antroquinonols in Antrodia cinnamomea.

Applied microbiology and biotechnology - 1 Jun 2017

Yu Po-Wei, Cho Ting-Yu, Liou Ruey-Fen, Tzean Shean-Shong, Lee Tzong-Huei

Abstract excerpt

Antrodia cinnamomea, an endemic basidiomycete used as a health food in Taiwan, is known to synthesize antroquinonols, which were reported to have notable medicinal potential in oncology and immunology. However, the biosynthetic pathway of these compounds is currently unclear. Our previous study showed that a pks63787 knockout mutant of A. cinnamomea (∆pks63787) is deficient in the biosynthesis of several aromatic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Polyketide Synthases
Share to Taiwan

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biological Products

Share to Biosynthetic Pathways

Share to Fruiting Bodies, Fungal

Share to Gene Knockout Techniques

Share to Molecular Structure

Share to Ubiquinone

Source

Identifiers

PMID: 28255687
DOI: 10.1007/s00253-017-8196-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of the orsellinic acid synthase PKS63787 for the biosynthesis of antroquinonols in Antrodia cinnamomea.PMID 28255687Read ↗

High-efficient production of mushroom polyketide compounds in a platform host Aspergillus oryzaeSemantic proximity Read ↗

Epoxinnamide: An Epoxy Cinnamoyl-Containing Nonribosomal Peptide from an Intertidal Mudflat-Derived Streptomyces sp.Semantic proximity Read ↗

p-Aminophenylalanine Involved in the Biosynthesis of Antitumor Dnacin B1 for Quinone Moiety Formation.Semantic proximity Read ↗

Fusarium graminearum PKS14 is involved in orsellinic acid and orcinol synthesis.Semantic proximity Read ↗

Genetics of Polyketide Metabolism in Aspergillus nidulansSemantic proximity Read ↗

Characterization of a Prenyltransferase for Iso-A82775C Biosynthesis and Generation of New Congeners of ChloropestolidesSemantic proximity Read ↗

The integration of metabolome and proteome reveals bioactive polyphenols and hispidin in ARTP mutagenized Phellinus baumii.Semantic proximity Read ↗

Genome-wide characterization and metabolite profiling of Cyathus olla: insights into the biosynthesis of medicinal compoundsSemantic proximity Read ↗

Recent advances in biosynthesis of bioactive compounds in traditional Chinese medicinal plantsSemantic proximity Read ↗

Development and analysis of de novo transcriptome assemblies of multiple genotypes of Cymbopogon spp. reveal candidate genes involved in the biosynthesis of aromatic monoterpenes.Semantic proximity Read ↗

Genome Mining and Screening for Secondary Metabolite Production in the Endophytic Fungus Dactylonectria alcacerensis CT-6Semantic proximity Read ↗

Genome mining and biosynthesis of kitacinnamycins as a STING activatorSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.