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Article

An assay suitable for high throughput screening of anti-influenza drugs.

PloS one - 1 Jan 2013

Mao Lili, Wang Jun, DeGrado William F, Inouye Masayori

Abstract excerpt

We developed a novel drug screening system for anti-influenza A virus by targeting the M2 proton channel. In the SPP (Single Protein Production) system, E. coli cell growth occurs only in the presence of effective M2 channel inhibitors, and thus simple measurement of cell growth was used as reado...

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Share to Antiviral Agents
Share to Drug Evaluation, Preclinical
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to High-Throughput Screening Assays

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Identifiers

PMID: 23326573
DOI: 10.1371/journal.pone.0054070
PMCID: PMC3542334

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23326573-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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