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Article

Nuclear legumain activity in colorectal cancer.

PloS one - 1 Jan 2013

Haugen Mads H, Johansen Harald T, Pettersen Solveig J, Solberg Rigmor, Brix Klaudia, Flatmark Kjersti, Maelandsmo Gunhild M

Abstract excerpt

The cysteine protease legumain is involved in several biological and pathological processes, and the protease has been found over-expressed and associated with an invasive and metastatic phenotype in a number of solid tumors. Consequently, legumain has been proposed as a prognostic marker for cer...

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Identifiers

PMID: 23326369
DOI: 10.1371/journal.pone.0052980
PMCID: PMC3542341

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23326369-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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