Transgelins: Cytoskeletal Associated Proteins Implicated in the Metastasis of Colorectal Cancer

Abstract excerpt

Actin-binding proteins (ABPs) are proteins that could bind to actin or actin fibers.As a family of actin-binding proteins , the transgelins can change the structure and morphology of the cytoskeleton by binding actin directly.The transgelin family comprises transgelin-1,transgelin-2 and transgelin-3 three isoforms,they are both directly and indirectly involved in many cancer-related processes such as migration,...

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