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Article

Clinicopathologic and prognostic significance of matrilysin expression at the invasive front in human colorectal cancers

1 Jan 2001

Abstract excerpt

Matrix metalloproteinases (MMPs) have been implicated in tumor progression. Matrilysin, one of the matrix metalloproteinases, is frequently overexpressed in gastrointestinal cancers. The aim of our study was to assess the validity of matrilysin as a prognostic marker of colorectal cancers. Matrilysin expression was immunohistochemically analyzed using formalin-fixed, paraffin-embedded specimens from 113...

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PMID: 11494227
DOI: 10.1002/1097-0215(20010920)95:5<290::aid-ijc1050>3.0.co;2-i

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