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Article

The influence of hydroxyurea on oxidative stress in sickle cell anemia

1 Jan 2012

Abstract excerpt

OBJECTIVE: The oxidative stress in 20 sickle cell anemia patients taking hydroxyurea and 13 sickle cell anemia patients who did not take hydroxyurea was compared with a control group of 96 individuals without any hemoglobinopathy. METHODS: Oxidative stress was assessed by thiobarbituric acid reactive species production, the Trolox-equivalent antioxidant capacity and plasma glutathione levels. RESULTS:...

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PMID: 23323065
DOI: 10.5581/1516-8484.20120106

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