Article
Identification of a candidate gene for astigmatism.
Investigative ophthalmology & visual science - 1 Feb 2013
Lopes Margarida C, Hysi Pirro G, Verhoeven Virginie J M, Macgregor Stuart, Hewitt Alex W, Montgomery Grant W, Cumberland Phillippa, Vingerling Johannes R, Young Terri L, van Duijn Cornelia M, Oostra Ben, Uitterlinden Andre G, Rahi Jugnoo S, Mackey David A, Klaver Caroline C W, Andrew Toby, Hammond Christopher J
Abstract excerpt
PURPOSE: Astigmatism is a common refractive error that reduces vision, where the curvature and refractive power of the cornea in one meridian are less than those of the perpendicular axis. It is a complex trait likely to be influenced by both genetic and environmental factors. Twin studies of astigmatism have found approximately 60% of phenotypic variance is explained by genetic factors. This study aimed to...
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