Article
Characterization of Escherichia coli D-cycloserine transport and resistant mutants.
Journal of bacteriology - 1 Apr 2013
Baisa Gary, Stabo Nicholas J, Welch Rodney A
Abstract excerpt
d-Cycloserine (DCS) is a broad-spectrum antibiotic that inhibits d-alanine ligase and alanine racemase activity. When Escherichia coli K-12 or CFT073 is grown in minimal glucose or glycerol medium, CycA transports DCS into the cell. E. coli K-12 cycA and CFT073 cycA mutant strains display increas...
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