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Article

Validating MARK2 Gene Polymorphism as a Predictor of Response to Lithium Treatment in Bipolar Patients

Iranian biomedical journal - 1 Mar 2022

Aghabozorg Afjeh Sara Sadat, Shams Jamal, Hamednia Safar, Boshehri Behzad, Amini Asmaolhosna, Omrani Amin, Omrani Mir Davood

Abstract excerpt

Background: Lithium is a therapeutic option for the treatment of the acute phase of the bipolar disorder and long-term management of this disorder. However, it is estimated that 10 to 60% of patients do not properly response to this medication. Methods: To investigate the role of MARK2 gene in response to lithium, we genotyped the MARK2 rs10792421 polymorphism in Iranian bipolar patients using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34953473
DOI: 10.52547/ibj.26.2.110
PMCID: PMC8987413

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