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Clinical experience with fetal hemoglobin induction therapy in patients with β-thalassemia

12 Jan 2013

Abstract excerpt

Recent molecular studies of fetal hemoglobin (HbF) regulation have reinvigorated the field and shown promise for the development of clinical HbF inducers to be used in patients with β-thalassemia and sickle cell disease. However, while numerous promising inducers of HbF have been studied in the past in β-thalassemia patient populations, with limited success in some cases, no universally effective agents have been...

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PMID: 23315167
DOI: 10.1182/blood-2012-10-408021

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