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Article

Therapeutic Approaches to Hemoglobin Switching in Treatment of Hemoglobinopathies

1 Feb 1992

Abstract excerpt

The past decade has witnessed profound increases in knowledge of the structure, function, and developmental regulation of the human globin genes. This information has deepened our understanding of the molecular and cellular mechanisms underlying inherited disorders affecting hemoglobin, and it has provided a new perspective for attaining meaningful increases in fetal hemoglobin synthesis in the management of...

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Share to Hemoglobinopathies and Related Disorders
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PMID: 1374600
DOI: 10.1146/annurev.me.43.020192.002433

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