Article
Alternative splicing in the regulation of cholesterol homeostasis.
Current opinion in lipidology - 1 Apr 2013
Medina Marisa W, Krauss Ronald M
Abstract excerpt
PURPOSE OF REVIEW: With the advent of whole-transcriptome sequencing, or RNA-seq, we now know that alternative splicing is a generalized phenomenon, with nearly all multiexonic genes subject to alternative splicing. In this review, we highlight recent studies examining alternative splicing as a modulator of cellular cholesterol homeostasis and as an underlying mechanism of dyslipidemia. RECENT FINDINGS: A number...
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