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Article

The relevance of alternative RNA splicing to pharmacogenomics.

Trends in biotechnology - 1 Aug 2003

Bracco Laurent, Kearsey Jonathan

Abstract excerpt

The importance of alternative RNA splicing in the generation of genetic diversity is now widely accepted. This article highlights how alternative RNA splicing can have an impact on drug efficacy and safety, and demonstrates its potential pharmacogenomic value. The analysis of the repertoire of alternative RNA splicing events could potentially identify markers of pharmacogenomic relevance with high sensitivity and...

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PMID: 12902171
DOI: 10.1016/S0167-7799(03)00146-X

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