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Regulatory roles and mechanisms of alternative RNA splicing in adipogenesis and human metabolic health

1 Apr 2021

Abstract excerpt

Alternative splicing (AS) regulates gene expression patterns at the post-transcriptional level and generates a striking expansion of coding capacities of genomes and cellular protein diversity. RNA splicing could undergo modulation and close interaction with genetic and epigenetic machinery. Notably, during the adipogenesis processes of white, brown and beige adipocytes, AS tightly interplays with the...

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PMID: 33795017
DOI: 10.1186/s13578-021-00581-w

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