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Article

Alternative mRNA Splicing in the Pathogenesis of Obesity

23 Feb 2018

Abstract excerpt

Alternative mRNA splicing is an important mechanism in expansion of proteome diversity by production of multiple protein isoforms. However, emerging evidence indicates that only a limited number of annotated protein isoforms by alternative splicing are detected, and the coding sequence of alternative splice variants usually is only slightly different from that of the canonical sequence. Nevertheless, mis-splicing...

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PMID: 29473878
DOI: 10.3390/ijms19020632

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