Article
Genome-wide detection of alternative splicing in expressed sequences of human genes.
Nucleic acids research - 1 Jul 2001
Modrek B, Resch A, Grasso C, Lee C
Abstract excerpt
We have identified 6201 alternative splice relationships in human genes, through a genome-wide analysis of expressed sequence tags (ESTs). Starting with approximately 2.1 million human mRNA and EST sequences, we mapped expressed sequences onto the draft human genome sequence and only accepted splices that obeyed the standard splice site consensus. A large fraction (47%) of these were observed multiple times,...
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