Article
Clonal diversity of the stem cell compartment
5 Jun 2006
Abstract excerpt
PURPOSE OF REVIEW: Hematopoietic stem cells are functionally heterogeneous even when isolated as phenotypically homogenous populations. How this heterogeneity is generated is incompletely understood. Several models have been formulated to explain the generation of diversity. All of these assume the existence of a single type of hematopoietic stem cell that generates heterogeneous daughter stem cells in response...
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