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Article

Lack of association of the HMGA1 IVS5-13insC variant with type 2 diabetes in an ethnically diverse hypertensive case control cohort.

Journal of translational medicine - 9 Jan 2013

Karnes Jason H, Langaee Taimour Y, McDonough Caitrin W, Chang Shin-Wen, Ramos Miguel, Catlin James R, Casanova Octavio E, Gong Yan, Pepine Carl J, Johnson Julie A, Cooper-Dehoff Rhonda M

Abstract excerpt

BACKGROUND: Recently, the high-mobility group A1 gene (HMGA1) variant IVS5-13insC has been associated with type 2 diabetes, but reported associations are inconsistent and data are lacking in Hispanic and African American populations. We sought to investigate the HMGA1-diabetes association and to characterize IVS5-13insC allele frequencies and linkage disequilibrium (LD) in 3,070 Caucasian, Hispanic, and African...

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Source

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Identifiers

PMID: 23302499
DOI: 10.1186/1479-5876-11-12
PMCID: PMC3558451

Genes

HMGA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Lack of association of the HMGA1 IVS5-13insC variant with type 2 diabetes in an ethnically diverse hypertensive case control cohort.PMID 23302499Read ↗

Low-frequency variants in HMGA1 are not associated with type 2 diabetes risk.Semantic proximity Read ↗

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Evidence that an HMGA1 gene variant associates with type 2 diabetes, body mass index, and high-density lipoprotein cholesterol in a Hispanic-American population.Semantic proximity Read ↗

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Common variant in the HMGA2 gene increases susceptibility to nephropathy in patients with type 2 diabetes.Semantic proximity Read ↗

Polymorphisms in AHI1 are not associated with type 2 diabetes or related phenotypes in Danes: non-replication of a genome-wide association result.Semantic proximity Read ↗

A paucimorphic variant in the HMG-CoA reductase gene is associated with lipid-lowering response to statin treatment in diabetes: a GoDARTS study.Semantic proximity Read ↗

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Association between CDH13 variants and cardiometabolic and vascular phenotypes in a Korean population.Semantic proximity Read ↗

Common SNPs in HMGCR in micronesians and whites associated with LDL-cholesterol levels affect alternative splicing of exon13.Semantic proximity Read ↗

Vesicle-associated membrane protein 4, a positional candidate gene on 1q24-q25, is not associated with type 2 diabetes in the Old Order Amish.Semantic proximity Read ↗

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