Article
Structural requirements for cub domain containing protein 1 (CDCP1) and Src dependent cell transformation.
PloS one - 1 Jan 2012
Kollmorgen Gwendlyn, Bossenmaier Birgit, Niederfellner Gerhard, Häring Hans-Ulrich, Lammers Reiner
Abstract excerpt
Cub domain containing protein 1 (CDCP1) is strongly expressed in tumors derived from lung, colon, ovary, or kidney. It is a membrane protein that is phosphorylated and then bound by Src family kinases. Although expression and phosphorylation of CDCP1 have been investigated in many tumor cell lines, the CDCP1 features responsible for transformation have not been fully evaluated. This is in part due to the lack of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
