Article
Maturation of mouse mammary tumor virus envelope protein is blocked by a specific point mutation.
Virology - 1 Jul 1992
Bedgood R M, Snider L D, Stallcup M R
Abstract excerpt
Expression of a mouse mammary tumor virus (MMTV) envelope gene, ENV2, in COS-7 cells resulted in the synthesis of a precursor protein Pr74 that underwent complete proteolytic processing to the mature envelope species gp52 and gp33. In contrast, expression of a second MMTV envelope gene, ENV1, in COS-7 cells resulted in the synthesis of a precursor protein Pr74 that failed to undergo proteolytic processing to the...
Topics
- Animals
- Cells, Cultured
- Genes, env
- Mammary Tumor Virus, Mouse
- Mutation
- Protein Precursors
- Protein Processing, Post-Translational
- Viral Envelope Proteins