Article
Overexpression, crystallization and preliminary X-ray crystallographic analysis of the variable lymphocyte receptor 2913 ectodomain fused with internalin B.
Acta crystallographica. Section F, Structural biology and crystallization communications - 1 Jan 2013
Lee Ji Yeon, Kim Hyoun Sook, Baek In Wha, Back Jang Mi, Han Mi Ra, Kong Sun Young, Kim Ji Hyeon, Kirchdoerfer Robert N, Kim Jae Ouk, Cooper Max D, Wilson Ian A, Kim Hyun-Jung, Han Byung Woo
Abstract excerpt
In jawless vertebrates, variable lymphocyte receptors (VLRs) play a crucial role in the recognition of antigens as part of the adaptive immune system. Leucine-rich repeat (LRR) modules and the highly variable insert (HVI) of VLRs contribute to the specificity and diversity of antigen recognition. VLR2913, the antigen of which is not known, contains the same HVI amino-acid sequence as that of VLR RBC36, which...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.