Article
High expression of the RNA-binding protein RBPMS2 in gastrointestinal stromal tumors.
Experimental and molecular pathology - 1 Apr 2013
Hapkova Ilona, Skarda Josef, Rouleau Caroline, Thys An, Notarnicola Cécile, Janikova Maria, Bernex Florence, Rypka Miroslav, Vanderwinden Jean-Marie, Faure Sandrine, Vesely Jaroslav, de Santa Barbara Pascal
Abstract excerpt
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract and are often associated with KIT or PDGFRA gene mutations. GIST cells might arise from the interstitial cells of Cajal (ICCs) or from a mesenchymal precursor that is common to ICCs and smooth muscle cells (SMCs). Here, we analyzed the mRNA and protein expression of RNA-Binding Protein with Multiple...
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