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Article

Prognostic role of E2F1 and members of the CDKN2A network in gastrointestinal stromal tumors.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Sept 2005

Haller Florian, Gunawan Bastian, von Heydebreck Anja, Schwager Stefanie, Schulten Hans-Jürgen, Wolf-Salgó Judith, Langer Claus, Ramadori Giuliano, Sültmann Holger, Füzesi László

Abstract excerpt

PURPOSE: The aim of the current study was to examine the prognostic relevance of the CDKN2A tumor suppressor pathway in gastrointestinal stromal tumors (GIST). EXPERIMENTAL DESIGN: We determined the mRNA expression of p1(INK4A), p14(ARF), CDK4, RB1, MDM2, TP53, and E2F1 by quantitative reverse transcription-PCR in 38 cases of GISTs and correlated the findings with clinicopathologic factors, including mutation...

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Source

Identifiers

PMID: 16166437
DOI: 10.1158/1078-0432.CCR-05-0329

Genes

CDK4
KIT
MDM2
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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