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Article

Optimal age to start preventive measures in women with BRCA1/2 mutations or high familial breast cancer risk.

International journal of cancer - 1 Jul 2013

Tilanus-Linthorst Madeleine M A, Lingsma Hester F, Evans D Gareth, Thompson Deborah, Kaas Reinoutje, Manders Peggy, van Asperen Christi J, Adank Muriel, Hooning Maartje J, Kwan Lim Gek E, Eeles Rosalind, Oosterwijk Jan C, Leach Martin O, Steyerberg Ewout W

Abstract excerpt

Women from high-risk families consider preventive measures for breast cancer including screening. Guidelines on screening differ considerably regarding starting age. We investigated whether age at diagnosis in affected relatives is predictive for age at diagnosis. We analyzed the age of breast cancer detection of 1,304 first- and second-degree relatives of 314 BRCA1, 164 BRCA2 and 244 high-risk participants of...

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Identifiers

PMID: 23292943
DOI: 10.1002/ijc.28014

Genes

BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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