Article
Evaluation of 16 SNPs allele-specific to quantify post hSCT chimerism by SYBR green-based qRT-PCR.
Journal of clinical pathology - 1 Mar 2013
Almeida Carlos Arthur Cardoso, Dreyfuss Juliana Luporini, Azevedo-Shimmoto Marily Maria, Figueiredo Maria Stela, de Oliveira José Salvador Rodrigues
Abstract excerpt
The importance of monitoring post haematopoietic stem cell transplantation (hSCT) chimerism has been defined in numerous publications. Single-nucleotide polymorphisms (SNPs) are molecular markers that vary significantly among different populations. Allied to a very sensible technique, SNP assays seem to be very sensitive (0.001%) when post hSCT chimerism is measured. However, well known SNP frequencies are...
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