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"HLA-10-SNP": A new qPCR-based system for rapid, effective, and accurate detection of 10 important SNPs in the HLA region.

HLA - 1 Nov 2021

Zheng Zhong-Zheng, Li Dai-Yang, Du Ke-Ming, Xu Xiang, Wang Ning-Juan, Yuan Zhi-Yang, Li Bo-An

Abstract excerpt

Mastering the SNP content in the HLA region can be based on it to judiciously select unrelated donor stem cells with preferable MHC matching to lower postoperative complications. Herein, quantitative PCR-based primers and probes were designed for 10 transplants outcome-associated SNP loci with two-allelic polymorphism, and then a new detection system ("HLA-10-SNP") was established. Compared with Sanger...

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PMID: 34375029
DOI: 10.1111/tan.14396

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