Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Self-glycolipids modulate dendritic cells changing the cytokine profiles of committed autoreactive T cells.

PloS one - 1 Jan 2012

Buschard Karsten, Månsson Jan-Eric, Roep Bart O, Nikolic Tatjana

Abstract excerpt

The impact of glycolipids of non-mammalian origin on autoimmune inflammation has become widely recognized. Here we report that the naturally occurring mammalian glycolipids, sulfatide and β-GalCer, affect the differentiation and the quality of antigen presentation by monocyte-derived dendritic cells (DCs). In response to sulfatide and β-GalCer, monocytes develop into immature DCs with higher expression of HLA-DR...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmunity
Share to Cell Differentiation
Share to Cytokines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dendritic Cells

Share to Glycolipids

Share to T-Lymphocytes

Share to Toll-Like Receptor 2

Share to Toll-Like Receptor 4

Source

Open in PubMed Open full text

Identifiers

PMID: 23285123
DOI: 10.1371/journal.pone.0052639
PMCID: PMC3527583

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Self-glycolipids modulate dendritic cells changing the cytokine profiles of committed autoreactive T cells.PMID 23285123Read ↗

CD1d-restricted glycolipid antigens: presentation principles, recognition logic and functional consequences.Semantic proximity Read ↗

Type II NKT-TFH cells against Gaucher lipids regulate B-cell immunity and inflammationSemantic proximity Read ↗

Evidence for a link between sphingolipid metabolism and expression of CD1d and MHC‐class II: monocytes from Gaucher disease patients as a modelSemantic proximity Read ↗

PD-1/PD-L blockade prevents anergy induction and enhances the anti-tumor activities of glycolipid-activated invariant NKT cells.Semantic proximity Read ↗

Dendritic cells in central nervous system autoimmunity.Semantic proximity Read ↗

Granulocyte-macrophage colony-stimulating factor may contribute to spondyloarthritis development in HLA-B27 transgenic rat by affecting conventional dendritic cells functionSemantic proximity Read ↗

Hyposialylation Must Be Considered to Develop Future Therapies in Autoimmune DiseasesSemantic proximity Read ↗

[The role of human 6-sulfo LacNAc dendritic cells (slanDCs) in autoimmunity and tumor diseases].Semantic proximity Read ↗

Sirt6 regulates dendritic cell differentiation, maturation, and function.Semantic proximity Read ↗

O-GlcNAcylation and low glycolysis underpin Th2 polarization by dendritic cellsSemantic proximity Read ↗

Immunomodulatory Dual-Sized Microparticle System Conditions Human Antigen Presenting Cells Into a Tolerogenic Phenotype In Vitro and Inhibits Type 1 Diabetes-Specific Autoreactive T Cell Responses.Semantic proximity Read ↗

Regulatory function of glycosphingolipids in the inflammation and degeneration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.