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Article

The ESX-5 associated eccB-EccC locus is essential for Mycobacterium tuberculosis viability.

PloS one - 1 Jan 2012

Di Luca Mariagrazia, Bottai Daria, Batoni Giovanna, Orgeur Mickael, Aulicino Anna, Counoupas Claudio, Campa Mario, Brosch Roland, Esin Semih

Abstract excerpt

The recently described ESX-5 secretion system of Mycobacterium tuberculosis is one of the most important modulators of host-pathogen interactions due to its crucial impact on PPE protein secretion, cell wall stability and virulence. Although various components of the ESX-5 secretion machinery have been defined, other ESX-5 core components still remain to be characterized. In this study, we focused on EccB(5) and...

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Source

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Identifiers

PMID: 23284869
DOI: 10.1371/journal.pone.0052059
PMCID: PMC3524121

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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