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Article

Micro-scale genomic DNA copy number aberrations as another means of mutagenesis in breast cancer.

PloS one - 1 Jan 2012

Chao Hann-Hsiang, He Xiaping, Parker Joel S, Zhao Wei, Perou Charles M

Abstract excerpt

INTRODUCTION: In breast cancer, the basal-like subtype has high levels of genomic instability relative to other breast cancer subtypes with many basal-like-specific regions of aberration. There is evidence that this genomic instability extends to smaller scale genomic aberrations, as shown by a previously described micro-deletion event in the PTEN gene in the Basal-like SUM149 breast cancer cell line. METHODS: We...

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Identifiers

PMID: 23284754
DOI: 10.1371/journal.pone.0051719
PMCID: PMC3524128

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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