Article
Mutational analysis of splicing machinery genes SF3B1, U2AF1 and SRSF2 in myelodysplasia and other common tumors.
International journal of cancer - 1 Jul 2013
Je Eun Mi, Yoo Nam Jin, Kim Yoo Jin, Kim Myung Shin, Lee Sug Hyung
Abstract excerpt
Recurrent somatic mutations in splicing machinery components, including SF3B1, U2AF1 and SRSF2 genes have recently been reported in myelodysplastic syndromes (MDS). Such a recurrent nature strongly suggests that these mutations play important roles in tumor development. To see whether SF3B1, U2AF...
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