Article
Mitochondrial genetics and osteoarthritis.
Frontiers in bioscience (Scholar edition) - 1 Jan 2013
Rego-Perez Ignacio, Fernandez-Moreno Mercedes, Soto-Hermida Angel, Fenandez-Lopez Carlos, Oreiro Natividad, Blanco Francisco J
Abstract excerpt
The genetic contribution is one of the most notable factors that play a main role in the risk of OA. Despite the genetics of this disease is complex and the finding of risk-related genes has been very challenging, evidence for genetic predisposition has been reported. Besides, in the last years recent evidences indicate that the mitochondrion is implicated in OA. In this context, the mtDNA haplogroups, defined as...
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