Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of mitochondria in osteoarthritis.

Nature reviews. Rheumatology - 1 Mar 2011

Blanco Francisco J, Rego Ignacio, Ruiz-Romero Cristina

Abstract excerpt

Mitochondria are important regulators of cellular function and survival that may have a key role in aging-related diseases. Mitochondrial DNA (mtDNA) mutations and oxidative stresses are known to contribute to aging-related changes. Osteoarthritis (OA) is an aging-associated rheumatic disease characterized by articular cartilage degradation and elevated chondrocyte mortality. Articular cartilage chondrocytes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chondrocytes
Share to DNA, Mitochondrial
Share to Mitochondria

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Osteoarthritis

Source

Identifiers

PMID: 21200395
DOI: 10.1038/nrrheum.2010.213

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of mitochondria in osteoarthritis.PMID 21200395Read ↗

Mitochondrial DNA variation and the pathogenesis of osteoarthritis phenotypes.Semantic proximity Read ↗

The role and intervention of mitochondrial metabolism in osteoarthritisSemantic proximity Read ↗

Mitochondrial Genetics and Epigenetics in OsteoarthritisSemantic proximity Read ↗

Mitochondrial genetics and osteoarthritis.Semantic proximity Read ↗

Mitochondria: Potential Targets for OsteoarthritisSemantic proximity Read ↗

Mitochondrial Biogenesis, Activity, and DNA Isolation in Chondrocytes.Semantic proximity Read ↗

Mitochondrial DNA haplogroups modify the risk of osteoarthritis by altering mitochondrial function and intracellular mitochondrial signalsSemantic proximity Read ↗

How are Aging and Osteoarthritis Related?Semantic proximity Read ↗

Apoptosis signaling pathways in osteoarthritis and possible protective role of melatoninSemantic proximity Read ↗

Correlation between circulating cell-free mitochondrial DNA content and severity of knee degeneration in patients with knee osteoarthritis: a cross-sectional studySemantic proximity Read ↗

Mitochondrial Dysfunction in Chronic Obstructive Pulmonary Disease: Unraveling the Molecular NexusSemantic proximity Read ↗

The Pathophysiological Role of Mitochondrial Oxidative Stress in Rheumatic DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.