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Article

Mitochondrial Haplogroups Define Two Phenotypes of Osteoarthritis

1 Jan 2012

Abstract excerpt

OBJECTIVE: To assess a mitochondrion-related phenotype in patients with osteoarthritis (OA). METHODS: Serum levels of the following OA-related biomarkers: matrix metalloproteinase-1 (MMP-1); MMP-3; MMP-13; myeloperoxidase (MPO); a peptide of the alpha-helical region of type II collagen, Coll2-1, and its nitrated form Coll2-1NO(2); a C-terminal neoepitope generated by the collagenase-mediated cleavage of collagen...

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Identifiers

PMID: 22593743
DOI: 10.3389/fphys.2012.00129

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