Article
Role of mtDNA haplogroups in the prevalence of knee osteoarthritis in a southern Chinese population.
International journal of molecular sciences - 14 Feb 2014
Fang Hezhi, Liu Xinwei, Shen Lijun, Li Fengjie, Liu Yihong, Chi Hongbo, Miao Huikai, Lu Jianxin, Bai Yidong
Abstract excerpt
Mitochondrial DNA (mtDNA) has been implicated in various human degenerative diseases. However, the role of mtDNA in Osteoarthritis (OA) is less known. To investigate whether mtDNA haplogroups contribute to the prevalence of knee OA, we have carried out a comprehensive case-control study on 187 knee OA patients and 420 geographically matched controls in southern China. OA patients were classified on the...
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