Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TGM2 and implications for human disease: role of alternative splicing

31 Dec 2012

Abstract excerpt

Alternative splicing is an important mechanism for modulating gene function that accounts for a considerable proportion of proteomic complexity in higher eukaryotes. Alternative splicing is often tightly regulated in a cell-type- or developmental-stage- specific manner and can cause a single gene to have multiple functions. Human Tissue transglutaminase (TGM2) is a multifunctional enzyme with transglutaminase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood properties and coagulation

Source

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 23276939
DOI: 10.2741/4117

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TGM2 and implications for human disease: role of alternative splicingPMID 23276939Read ↗

Expression of transglutaminase-2 isoforms in normal human tissues and cancer cell lines: dysregulation of alternative splicing in cancerSemantic proximity Read ↗

The Role of Transglutaminase 2 in Cancer: An UpdateSemantic proximity Read ↗

Polymorphism of transglutaminase 2: unusually low frequency of genomic variants with deficient functions.Semantic proximity Read ↗

Transglutaminases and their substrates in biology and human diseases: 50 years of growingSemantic proximity Read ↗

Transglutaminase 3: The Involvement in Epithelial Differentiation and CancerSemantic proximity Read ↗

Transglutaminase 2 takes center stage as a cancer cell survival factor and therapy targetSemantic proximity Read ↗

Transglutaminase 2 is an RNA-binding protein: Experimental verification and characterisation of a novel transglutaminase featureSemantic proximity Read ↗

Tissue transglutaminase: from biological glue to cell survival cues.Semantic proximity Read ↗

Functional roles of alternative splicing factors in human disease.Semantic proximity Read ↗

Functional characterization of naturally occurring transglutaminase 2 mutants implicated in early-onset type 2 diabetes.Semantic proximity Read ↗

The role of transglutaminase-2 and its substrates in human diseases.Semantic proximity Read ↗

Genomic variants reveal differential evolutionary constraints on human transglutaminases and point towards unrecognized significance of transglutaminase 2.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.