Polymorphism of transglutaminase 2: unusually low frequency of genomic variants with deficient functions.

Abstract excerpt

Transglutaminase 2 (TG2) is a multifunctional member of an enzyme family: it modifies glutamine residues by cross-linking proteins and incorporating primary amines into them, has protein disulphide isomerase and protein kinase activities, mediates trans-membrane signal transduction and interactions between cell surface proteins and the extracellular matrix. These unusual multiple roles encoded into one...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Enzyme Stability
• Share to Fibronectins
• Share to Genome, Human