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Article

The effect of the composition of PLA films and lactate release on glial and neuronal maturation and the maintenance of the neuronal progenitor niche.

Biomaterials - 1 Mar 2013

Álvarez Zaida, Mateos-Timoneda Miguel A, Hyroššová Petra, Castaño Oscar, Planell Josep A, Perales José C, Engel Elisabeth, Alcántara Soledad

Abstract excerpt

To develop tissue engineering strategies useful for repairing damage in the central nervous system (CNS) it is essential to design scaffolds that emulate the NSC niche and its tight control of neural cell genesis, growth, and differentiation. In this study we tested two types of poly L/DL lactic acid (PLA95/5 and PLA70/30), a biodegradable material permissive for neural cell adhesion and growth, as materials for...

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Identifiers

PMID: 23276659
DOI: 10.1016/j.biomaterials.2012.12.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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