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Article

Exploiting natural polysaccharides to enhance in vitro bio-constructs of primary neurons and progenitor cells.

Acta biomaterialia - 1 Jun 2018

Medelin Manuela, Porrelli Davide, Aurand Emily Rose, Scaini Denis, Travan Andrea, Borgogna Massimiliano Antonio, Cok Michela, Donati Ivan, Marsich Eleonora, Scopa Chiara, Scardigli Raffaella, Paoletti Sergio, Ballerini Laura

Abstract excerpt

Current strategies in Central Nervous System (CNS) repair focus on the engineering of artificial scaffolds for guiding and promoting neuronal tissue regrowth. Ideally, one should combine such synthetic structures with stem cell therapies, encapsulating progenitor cells and instructing their differentiation and growth. We used developments in the design, synthesis, and characterization of polysaccharide-based...

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PMID: 29621637
DOI: 10.1016/j.actbio.2018.03.041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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