Article
Assessing the genome-wide effect of promoter region tandem repeat natural variation on gene expression.
G3 (Bethesda, Md.) - 1 Dec 2012
Elmore Martha H, Gibbons John G, Rokas Antonis
Abstract excerpt
Copy number polymorphisms of nucleotide tandem repeat (TR) regions, such as microsatellites and minisatellites, are mutationally reversible and highly abundant in eukaryotic genomes. Studies linking TR polymorphism to phenotypic variation have led some to suggest that TR variation modulates and majorly contributes to phenotypic variation; however, studies in which the authors assess the genome-wide impact of TR...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.