Article
Gene expression divergence in yeast is coupled to evolution of DNA-encoded nucleosome organization.
Nature genetics - 1 Apr 2009
Field Yair, Fondufe-Mittendorf Yvonne, Moore Irene K, Mieczkowski Piotr, Kaplan Noam, Lubling Yaniv, Lieb Jason D, Widom Jonathan, Segal Eran
Abstract excerpt
Eukaryotic transcription occurs within a chromatin environment, whose organization has an important regulatory function and is partly encoded in cis by the DNA sequence itself. Here, we examine whether evolutionary changes in gene expression are linked to changes in the DNA-encoded nucleosome org...
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