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Article

A targeted in vivo RNAi screen reveals deubiquitinases as new regulators of Notch signaling.

G3 (Bethesda, Md.) - 1 Dec 2012

Zhang Junzheng, Liu Min, Su Ying, Du Juan, Zhu Alan Jian

Abstract excerpt

Notch signaling is highly conserved in all metazoan animals and plays critical roles in cell fate specification, cell proliferation, apoptosis, and stem cell maintenance. Although core components of the Notch signaling cascade have been identified, many gaps in the understanding of the Notch signaling pathway remain to be filled. One form of posttranslational regulation, which is controlled by the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23275879
DOI: 10.1534/g3.112.003780
PMCID: PMC3516478

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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