Article
Differentiation-driven nucleolar association of the mouse imprinted Kcnq1 locus.
G3 (Bethesda, Md.) - 1 Dec 2012
Fedoriw Andrew M, Calabrese J Mauro, Mu Weipeng, Yee Della, Magnuson Terry
Abstract excerpt
The organization of the genome within the mammalian nucleus is nonrandom, with physiologic processes often concentrated in specific three-dimensional domains. This organization may be functionally related to gene regulation and, as such, may play a role in normal development and human disease processes. However, the mechanisms that participate in nuclear organization are poorly understood. Here, we present data...
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