Article
Telomeric NAP1L4 and OSBPL5 of the KCNQ1 cluster, and the DECORIN gene are not imprinted in human trophoblast stem cells.
PloS one - 14 Jul 2010
Frost Jennifer M, Udayashankar Ramya, Moore Harry D, Moore Gudrun E
Abstract excerpt
BACKGROUND: Genomic imprinting of the largest known cluster, the Kcnq1/KCNQ1 domain on mChr7/hChr11, displays significant differences between mouse and man. Of the fourteen transcripts in this cluster, imprinting of six is ubiquitous in mice and humans, however, imprinted expression of the other eight transcripts is only found in the mouse placenta. The human orthologues of the latter eight transcripts are...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.