Genetic and molecular insights into the role of PROX1 in glucose metabolism.

doi:10.2337/db12-0864

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Article

Genetic and molecular insights into the role of PROX1 in glucose metabolism.

Diabetes - 1 May 2013

Lecompte Sophie, Pasquetti Gianni, Hermant Xavier, Grenier-Boley Benjamin, Gonzalez-Gross Marcela, De Henauw Stephan, Molnar Denes, Stehle Peter, Béghin Laurent, Moreno Luis A, Amouyel Philippe, Dallongeville Jean, Meirhaeghe Aline

Abstract excerpt

Genome-wide association studies have shown that the rs340874 single nucleotide polymorphism (SNP) in PROX1 is a genetic susceptibility factor for type 2 diabetes. We conducted genetic and molecular studies to better understand the role of PROX1 in type 2 diabetes. We assessed the impact of the whole common genetic variability of PROX1 (80 SNPs) on type 2 diabetes-related biochemical traits in the HELENA (Healthy...

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PMID: 23274905
DOI: 10.2337/db12-0864
PMCID: PMC3636631

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PROX1
INS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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