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Article

Interaction between novelty seeking and the aldehyde dehydrogenase 2 gene in heroin-dependent patients.

Journal of clinical psychopharmacology - 1 Jun 2013

Lee Sheng-Yu, Wang Tzu-Yun, Chen Shiou-Lan, Huang San-Yuan, Tzeng Nian-Sheng, Chang Yun-Hsuan, Wang Chen-Lin, Wang Yu-Shan, Lee I Hui, Yeh Tzung Lieh, Yang Yen Kuang, Lu Ru-Band

Abstract excerpt

OBJECTIVES: Heroin dependence is a multifactor disorder. We investigated the association of genetic factors and heroin-dependent temperaments to determine whether a temperament-gene interaction is involved in the pathogenesis of heroin dependence. METHODS: Three hundred seventy participants (259 heroin-dependent patients and 111 healthy controls) were recruited and finished the Tridimensional Personality...

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Source

Identifiers

PMID: 23609397
DOI: 10.1097/JCP.0b013e3182900fb3

Genes

ALDH2
BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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