Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Systematic review and meta-analysis of serotonin transporter genotype and discontinuation from antidepressant treatment.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Oct 2013

Crawford Andrew A, Lewis Glyn, Lewis Sarah J, Munafò Marcus R

Abstract excerpt

There is evidence that 5-HTTLPR is associated with response following treatment from selective serotonin reuptake inhibitors (SSRIs). The short (S) allele has reduced serotonin transporter expression, compared to the long (L) allele, and has been reported to be associated with poorer response in Europeans, with the effect in other populations unclear. However the published literature is inconsistent. A systematic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antidepressive Agents
Share to Depression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance

Share to Evidence-Based Medicine

Share to Neurons

Share to Randomized Controlled Trials as Topic

Share to Selective Serotonin Reuptake Inhibitors

Share to Serotonin Plasma Membrane Transport Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 23265954
DOI: 10.1016/j.euroneuro.2012.12.001
PMCID: PMC3791403

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Systematic review and meta-analysis of serotonin transporter genotype and discontinuation from antidepressant treatment.PMID 23265954Read ↗

Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with antidepressant efficacy.Semantic proximity Read ↗

Serotonin Transporter Gene Polymorphisms and Selective Serotonin Reuptake Inhibitor Tolerability: Review of Pharmacogenetic EvidenceSemantic proximity Read ↗

The role of pharmacogenomics in the discontinuation of psychotropic medication: a scoping review protocolSemantic proximity Read ↗

The role of pharmacogenomics in the discontinuation of psychotropic medication: a scoping review protocolSemantic proximity Read ↗

Effects of the serotonin transporter gene promoter polymorphism on mirtazapine and paroxetine efficacy and adverse events in geriatric major depression.Semantic proximity Read ↗

Pharmacogenetics and the serotonin transporter in late-life depressionSemantic proximity Read ↗

Genotype influences antidepressant discontinuation in a pre-emptive pharmacogenetic testing population.Semantic proximity Read ↗

Antidepressant response and the serotonin transporter gene-linked polymorphic region.Semantic proximity Read ↗

Prediction of antidepressant side effects in the Genetic Link to Anxiety and Depression StudySemantic proximity Read ↗

The influence of 5-HTTLPR and STin2 polymorphisms in the serotonin transporter gene on treatment effect of selective serotonin reuptake inhibitors in depressive patients.Semantic proximity Read ↗

Association between serotonin transporter-linked polymorphic region and escitalopram antidepressant treatment response in Korean patients with major depressive disorder.Semantic proximity Read ↗

Serotonin transporter gene polymorphisms and treatment-resistant depression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.