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Article

Optimization of intradermal vaccination by DNA tattooing in human skin

25 Nov 2008

Abstract excerpt

The intradermal administration of DNA vaccines by tattooing is a promising delivery technique for genetic immunization, with proven high immunogenicity in mice and in nonhuman primates. However, the parameters that result in optimal expression of DNA vaccines that are applied by this strategy to human skin are currently unknown. To address this issue we set up an ex vivo human skin model in which DNA...

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Identifiers

PMID: 19301471
DOI: 10.1089/hgt.2008.073

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