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Article

Gene Transfer to Subdermal Tissues via a New Gene Gun Design

1 Jan 2003

Abstract excerpt

Although particle-mediated gene transfer technology (gene gun) has been applied for gene transfer to external tissues, the application of this technology to other tissues has met with limited success. Here we report the development of a new design of a gene gun that uses helium discharge to propel DNA-coated gold beads that are suspended in liquid. Higher discharge pressures allow for the delivery of DNA to...

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PMID: 12573061
DOI: 10.1089/10430340360464732

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